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Doctor Discussion Guide
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Antihistamines are important in the treatment of short-term hives (acute urticaria), a common symptom of allergic reactions

What are antihistamines?

An allergist or doctor will likely recommend an antihistamine for your hives. Antihistamines work by blocking the effect of histamine, a chemical released by the immune system that can cause allergic symptoms such as hives.

What potentially increases your risk for short-term hives?

Short-term hives from allergic reactions can result from various triggers, including but not limited to medications, blood transfusions, or viral infections. Patients with conditions such as rheumatoid arthritis, lupus, or cancer may be more likely to experience allergic reactions due to their prescribed treatments and medications.

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Are there different types of antihistamines?

There are two groups of antihistamines; both are prescribed in the treatment of hives, but there are differences.

1st generation

First-generation antihistamines, like diphenhydramine, work differently in the body and are often associated with side effects, such as drowsiness, and also have a higher potential to interact with other medications.

2nd generation

Second-generation antihistamines were chemically developed to lessen side effects of first-generation antihistamines, and also tend to have fewer interactions with other medications.

Tell your healthcare professional about all medicines you take, including prescription or over-the-counter medicines, vitamins, or herbal supplements.

About QUZYTTIR

Learn about the benefits of second-generation intravenous (IV) antihistamine QUZYTTIR for the treatment of your short-term hives.

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Important Safety Information
Who should NOT take QUZYTTIR?

DO NOT TAKE QUZYTTIR if you are allergic to any of its ingredients or if you are allergic to medications that contain levocetirizine or hydroxyzine.

What is the most important information that I should know about QUZYTTIR?

QUZYTTIR may cause serious side effects, including:

  • Sleepiness/Drowsiness. QUZYTTIR may cause you to feel sleepy. Be careful when driving a car or operating potentially dangerous machinery. Avoid alcohol or taking certain other medicines with QUZYTTIR, as this may raise your risk of having problems with alertness or thinking.
What should I tell my doctor before receiving treatment with QUZYTTIR?

Before taking QUZYTTIR tell your doctor:

  • About all of your medical conditions, including if you are pregnant, plan to become pregnant, or are breastfeeding.
  • About all medicines you take, including prescription or over-the-counter medicines, vitamins, or herbal supplements.
What are the possible side effects of QUZYTTIR?

The most common side effects include:

  • a metallic taste
  • headache
  • a tingling sensation
  • feeling faint
  • stomachache
  • feeling hot
  • excessive sweating

These are not all the possible side effects of QUZYTTIR. Be sure to contact your healthcare team right away if you have questions or are worried about any side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact ESTEVE Pharmaceuticals, S.A. at 1-888-306-6259 or drugsafety.us@esteve.com.

Please see accompanying Full Prescribing Information.

What is QUZYTTIR?

QUZYTTIR is an FDA-approved prescription medicine for the treatment of short-term hives (known as acute urticaria) for patients 6 months and older.

QUZYTTIR is not recommended if your child is younger than 6 years old with kidney or liver problems.

You are encouraged to report negative side effects of prescription drugs to the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact ESTEVE Pharmaceuticals, S.A. at 1-888-306-6259 or drugsafety.us@esteve.com.

Please see accompanying Full Prescribing Information.